Flavio Nervi Selected Research

Cholelithiasis

1/2020	Pathophysiological connections between gallstone disease, insulin resistance, and obesity.
9/2015	Effect of cholecystectomy on bile acid synthesis and circulating levels of fibroblast growth factor 19.
5/2012	Phytosterol and cholesterol precursor levels indicate increased cholesterol excretion and biosynthesis in gallstone disease.
2/2011	Apolipoprotein A-I deficiency does not affect biliary lipid secretion and gallstone formation in mice.
12/2009	Fecal bile acid excretion and messenger RNA expression levels of ileal transporters in high risk gallstone patients.
8/2008	Ezetimibe prevents cholesterol gallstone formation in mice.
8/2007	A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.
6/2007	Genetic evidence that apolipoprotein E4 is not a relevant susceptibility factor for cholelithiasis in two high-risk populations.
5/2007	Increased activity of hepatic microsomal triglyceride transfer protein and bile acid synthesis in gallstone disease.
12/2006	Inactivation of hepatic microsomal triglyceride transfer protein protects mice from diet-induced gallstones.

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Flavio Nervi Research Topics

Disease

19	Gallstones (Gallstone) 01/2018 - 04/2003
17	Cholelithiasis 01/2020 - 07/2002
6	Non-alcoholic Fatty Liver Disease 01/2018 - 01/2009
5	Insulin Resistance 01/2020 - 08/2006
4	Obesity 01/2020 - 06/2004
2	Fatty Liver 01/2020 - 01/2009
2	Atherosclerosis 11/2013 - 09/2003
2	Liver Cirrhosis (Hepatic Cirrhosis) 10/2011 - 10/2010
1	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2013
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2013
1	Hypertension (High Blood Pressure) 10/2011
1	Fibrosis (Cirrhosis) 10/2010
1	Type 2 Diabetes Mellitus (MODY) 10/2010
1	Neoplasms (Cancer) 12/2009
1	Hypercholesterolemia 06/2007
1	Cholestasis 06/2007
1	Death (Near-Death Experience) 04/2004
1	Gallbladder Neoplasms (Gallbladder Cancer) 07/2002

Drug/Important Bio-Agent (IBA)

22	CholesterolIBA 01/2020 - 04/2003
10	Bile Acids and Salts (Bile Acids)IBA 01/2020 - 09/2003
7	LipidsIBA 01/2020 - 09/2003
4	Lipoproteins (Lipoprotein)IBA 07/2010 - 09/2003
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 10/2010 - 01/2009
2	Alanine Transaminase (SGPT)IBA 10/2010 - 01/2009
2	Glucose (Dextrose)FDA LinkGeneric 10/2010 - 06/2007
2	Messenger RNA (mRNA)IBA 12/2009 - 05/2007
2	C-Reactive ProteinIBA 01/2009 - 08/2006
2	Scavenger Receptors (Scavenger Receptor)IBA 06/2007 - 06/2004
2	microsomal triglyceride transfer proteinIBA 05/2007 - 12/2006
2	Fatty Acids (Saturated Fatty Acids)IBA 05/2007 - 06/2004
2	O(4)-methylthymidine triphosphateIBA 05/2007 - 12/2006
1	Hormones (Hormone)IBA 01/2020
1	SterolsIBA 05/2012
1	Phytosterols (Plant Sterols)IBA 05/2012
1	Plasminogen InactivatorsIBA 10/2011
1	Plasminogen Activator Inhibitor 1IBA 10/2011
1	Triglycerides (Triacylglycerol)IBA 10/2011
1	HDL CholesterolIBA 02/2011
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 02/2011
1	LeptinIBA 10/2010
1	AdiponectinIBA 10/2010
1	Cholic AcidIBA 07/2010
1	Niemann-Pick C1 ProteinIBA 07/2010
1	Transaminases (Aminotransferases)IBA 01/2009
1	Insulin (Novolin)FDA Link 12/2008
1	Ezetimibe (Zetia)FDA Link 08/2008
1	Adenosine Triphosphate (ATP)IBA 06/2007
1	Apolipoprotein E4IBA 06/2007
1	Apolipoproteins E (ApoE)IBA 06/2007
1	Lipoprotein-XIBA 06/2007
1	Proteins (Proteins, Gene)FDA Link 05/2007
1	Phospholipids (Phosphatides)FDA LinkGeneric 12/2006
1	Estrogens (Estrogen)FDA Link 06/2004
1	Dietary CholesterolIBA 06/2004
1	CarbohydratesIBA 06/2004
1	MonosaccharidesIBA 06/2004
1	ApolipoproteinsIBA 06/2004
1	VitaminsIBA 06/2004
1	Orphan Nuclear ReceptorsIBA 06/2004
1	lathosterolIBA 03/2004
1	EnzymesIBA 03/2004
1	7 alpha-hydroxy-4-cholesten-3-oneIBA 03/2004
1	lipoprotein cholesterolIBA 09/2003
1	Lipase (Acid Lipase)FDA Link 09/2003

Therapy/Procedure

6	Cholecystectomy 01/2020 - 07/2002
1	Palliative Care (Palliative Therapy) 04/2004